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A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle
BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare idiopathic autoinflammatory bone disease that mostly affects children and adolescents. It is a diagnosis of exclusions since no clinical signs and symptoms are pathognomonic. Radiological tests are often essential, but bone biop...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717389/ https://www.ncbi.nlm.nih.gov/pubmed/31470834 http://dx.doi.org/10.1186/s12891-019-2776-9 |
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author | Świdrowska-Jaros, Joanna Smolewska, Elżbieta |
author_facet | Świdrowska-Jaros, Joanna Smolewska, Elżbieta |
author_sort | Świdrowska-Jaros, Joanna |
collection | PubMed |
description | BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare idiopathic autoinflammatory bone disease that mostly affects children and adolescents. It is a diagnosis of exclusions since no clinical signs and symptoms are pathognomonic. Radiological tests are often essential, but bone biopsy may be needed in unclear cases. CASE PRESENTATION: A 9-year-old Caucasian girl with a history of bone pain. The data from the history and results of laboratory tests suggested osteomyelitis, but no adequate response to the treatment was observed. A number of imaging tests did not confirm the diagnosis, therefore a bone biopsy was necessary. CONCLUSIONS: Differential diagnosis of CRMO is challenging and it is based on exclusions. Since it might be misdiagnosed or mistreated, bone biopsy should be considered in patients reporting bone pain who are unresponsive to treatment. |
format | Online Article Text |
id | pubmed-6717389 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-67173892019-09-06 A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle Świdrowska-Jaros, Joanna Smolewska, Elżbieta BMC Musculoskelet Disord Case Report BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare idiopathic autoinflammatory bone disease that mostly affects children and adolescents. It is a diagnosis of exclusions since no clinical signs and symptoms are pathognomonic. Radiological tests are often essential, but bone biopsy may be needed in unclear cases. CASE PRESENTATION: A 9-year-old Caucasian girl with a history of bone pain. The data from the history and results of laboratory tests suggested osteomyelitis, but no adequate response to the treatment was observed. A number of imaging tests did not confirm the diagnosis, therefore a bone biopsy was necessary. CONCLUSIONS: Differential diagnosis of CRMO is challenging and it is based on exclusions. Since it might be misdiagnosed or mistreated, bone biopsy should be considered in patients reporting bone pain who are unresponsive to treatment. BioMed Central 2019-08-31 /pmc/articles/PMC6717389/ /pubmed/31470834 http://dx.doi.org/10.1186/s12891-019-2776-9 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Świdrowska-Jaros, Joanna Smolewska, Elżbieta A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle |
title | A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle |
title_full | A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle |
title_fullStr | A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle |
title_full_unstemmed | A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle |
title_short | A complicated path to the CRMO diagnosis – case of a 9 year old girl whose story comes full circle |
title_sort | complicated path to the crmo diagnosis – case of a 9 year old girl whose story comes full circle |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717389/ https://www.ncbi.nlm.nih.gov/pubmed/31470834 http://dx.doi.org/10.1186/s12891-019-2776-9 |
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