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Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1): a target for cancer therapeutic intervention?

BACKGROUND: Cap-dependent mRNA translation is essential for the translation of key oncogenic proteins at optimal levels and is highly regulated by the rate limiting, initiation step in protein synthesis. Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) serves as a scaffold for assembly of...

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Detalles Bibliográficos
Autores principales:	Jaiswal, Praveen Kumar, Koul, Sweaty, Palanisamy, Nallasivam, Koul, Hari K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717390/ https://www.ncbi.nlm.nih.gov/pubmed/31496918 http://dx.doi.org/10.1186/s12935-019-0947-2

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