Minor intron splicing revisited: identification of new minor intron-containing genes and tissue-dependent retention and alternative splicing of minor introns

BACKGROUND: Mutations in minor spliceosome components such as U12 snRNA (cerebellar ataxia) and U4atac snRNA (microcephalic osteodysplastic primordial dwarfism type 1 (MOPD1)) result in tissue-specific symptoms. Given that the minor spliceosome is ubiquitously expressed, we hypothesized that these r...

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Detalles Bibliográficos
Autores principales: Olthof, Anouk M., Hyatt, Katery C., Kanadia, Rahul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717393/
https://www.ncbi.nlm.nih.gov/pubmed/31470809
http://dx.doi.org/10.1186/s12864-019-6046-x

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