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Methylation‐associated miR‐193b silencing activates master drivers of aggressive prostate cancer

Epigenetic silencing of miRNA is a primary mechanism of aberrant miRNA expression in cancer, and hypermethylation of miRNA promoters has been reported to contribute to prostate cancer initiation and progression. Recent data have shown that the miR‐193b promoter is hypermethylated in prostate cancer...

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Detalles Bibliográficos
Autores principales: Mazzu, Ying Z., Yoshikawa, Yuki, Nandakumar, Subhiksha, Chakraborty, Goutam, Armenia, Joshua, Jehane, Lina E., Lee, Gwo‐Shu Mary, Kantoff, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717747/
https://www.ncbi.nlm.nih.gov/pubmed/31225930
http://dx.doi.org/10.1002/1878-0261.12536

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