Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements

The loss of polycationic antimicrobial peptides, polymyxins, due to adhesion to plastics is an important subject matter that influences in vitro susceptibility testing, including minimum inhibitory concentration (MIC) assays. This review reminds us that this issue can serve as a significant source o...

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Detalles Bibliográficos
Autores principales: Sharafi, Toktam, Ardebili, Abdollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717857/
https://www.ncbi.nlm.nih.gov/pubmed/31695440
http://dx.doi.org/10.2147/IDR.S219130
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author Sharafi, Toktam
Ardebili, Abdollah
author_facet Sharafi, Toktam
Ardebili, Abdollah
author_sort Sharafi, Toktam
collection PubMed
description The loss of polycationic antimicrobial peptides, polymyxins, due to adhesion to plastics is an important subject matter that influences in vitro susceptibility testing, including minimum inhibitory concentration (MIC) assays. This review reminds us that this issue can serve as a significant source of variation in the MIC values for polymyxins against Gram-negative bacteria.
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spelling pubmed-67178572019-11-06 Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements Sharafi, Toktam Ardebili, Abdollah Infect Drug Resist Review The loss of polycationic antimicrobial peptides, polymyxins, due to adhesion to plastics is an important subject matter that influences in vitro susceptibility testing, including minimum inhibitory concentration (MIC) assays. This review reminds us that this issue can serve as a significant source of variation in the MIC values for polymyxins against Gram-negative bacteria. Dove 2019-08-27 /pmc/articles/PMC6717857/ /pubmed/31695440 http://dx.doi.org/10.2147/IDR.S219130 Text en © 2019 Sharafi and Ardebili. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Sharafi, Toktam
Ardebili, Abdollah
Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements
title Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements
title_full Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements
title_fullStr Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements
title_full_unstemmed Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements
title_short Plastic binding feature of polymyxins: the effect on MIC susceptibility measurements
title_sort plastic binding feature of polymyxins: the effect on mic susceptibility measurements
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717857/
https://www.ncbi.nlm.nih.gov/pubmed/31695440
http://dx.doi.org/10.2147/IDR.S219130
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