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SALM1 controls synapse development by promoting F‐actin/PIP2‐dependent Neurexin clustering
Synapse development requires spatiotemporally regulated recruitment of synaptic proteins. In this study, we describe a novel presynaptic mechanism of cis‐regulated oligomerization of adhesion molecules that controls synaptogenesis. We identified synaptic adhesion‐like molecule 1 (SALM1) as a constit...
Autores principales: | Brouwer, Marinka, Farzana, Fatima, Koopmans, Frank, Chen, Ning, Brunner, Jessie W, Oldani, Silvia, Li, Ka Wan, van Weering, Jan RT, Smit, August B, Toonen, Ruud F, Verhage, Matthijs |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717895/ https://www.ncbi.nlm.nih.gov/pubmed/31368584 http://dx.doi.org/10.15252/embj.2018101289 |
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