Cargando…

High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China

AIMS/INTRODUCTION: Diabetes prevalence in China has increased, but the trend in gestational diabetes mellitus prevalence is unclear. The objective of the present study was to examine the prevalence of gestational diabetes in Xiamen, China, and its association with maternal risk factors. MATERIALS AN...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Bing, Yu, Yaxin, Lin, Mingzhu, Li, Zhibin, Wang, Liying, Huang, Peiying, Song, Haiqu, Shi, Xiulin, Yang, Shuyu, Li, Xiaoying, Li, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717898/
https://www.ncbi.nlm.nih.gov/pubmed/30869198
http://dx.doi.org/10.1111/jdi.13039
_version_ 1783447637427486720
author Yan, Bing
Yu, Yaxin
Lin, Mingzhu
Li, Zhibin
Wang, Liying
Huang, Peiying
Song, Haiqu
Shi, Xiulin
Yang, Shuyu
Li, Xiaoying
Li, Xuejun
author_facet Yan, Bing
Yu, Yaxin
Lin, Mingzhu
Li, Zhibin
Wang, Liying
Huang, Peiying
Song, Haiqu
Shi, Xiulin
Yang, Shuyu
Li, Xiaoying
Li, Xuejun
author_sort Yan, Bing
collection PubMed
description AIMS/INTRODUCTION: Diabetes prevalence in China has increased, but the trend in gestational diabetes mellitus prevalence is unclear. The objective of the present study was to examine the prevalence of gestational diabetes in Xiamen, China, and its association with maternal risk factors. MATERIALS AND METHODS: This linked‐database cohort study used the Medical Birth Registry of Xiamen. Between 1 March 2011 and 30 March 2018, 78,572 women who were diagnosed with gestational diabetes mellitus (GDM) were enrolled in the study. Maternal factors associated with the prevalence of GDM were examined using multivariate logistic regression. RESULTS: A total of 13,738 (17.6%) pregnant women were diagnosed with GDM according to the International Association of Diabetes and Pregnancy Study Groups criteria. GDM prevalence ranged from 15.5% (2012) to 19.9% (2017). Increasing age was associated with GDM; women aged >40 years versus those aged >25 years had an adjusted odds ratio (OR) of 5.91 (95% confidence interval [CI] 4.202–8.314). A positive correlation was observed between weight and GDM risk; obese women versus normal‐weight women had an adjusted OR of 2.508 (95% CI 2.253–2.792). Family history of diabetes and hypertension were more commonly observed among women with GDM. Multivariate analysis showed that family history of diabetes (OR 1.101, 90% CI 1.028–1.180), weight gain during early pregnancy (OR 1.087, 90% CI 1.052–1.124) and systolic blood pressure (OR 1.015, 90% CI 1.011–1.020) were risk factors associated with GDM incidence. CONCLUSIONS: GDM affects 17.6% of all pregnant women in Xiamen. Age and maternal obesity were major contributors to GDM. The trend of GDM risk remained stable during the study.
format Online
Article
Text
id pubmed-6717898
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-67178982019-09-06 High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China Yan, Bing Yu, Yaxin Lin, Mingzhu Li, Zhibin Wang, Liying Huang, Peiying Song, Haiqu Shi, Xiulin Yang, Shuyu Li, Xiaoying Li, Xuejun J Diabetes Investig Articles AIMS/INTRODUCTION: Diabetes prevalence in China has increased, but the trend in gestational diabetes mellitus prevalence is unclear. The objective of the present study was to examine the prevalence of gestational diabetes in Xiamen, China, and its association with maternal risk factors. MATERIALS AND METHODS: This linked‐database cohort study used the Medical Birth Registry of Xiamen. Between 1 March 2011 and 30 March 2018, 78,572 women who were diagnosed with gestational diabetes mellitus (GDM) were enrolled in the study. Maternal factors associated with the prevalence of GDM were examined using multivariate logistic regression. RESULTS: A total of 13,738 (17.6%) pregnant women were diagnosed with GDM according to the International Association of Diabetes and Pregnancy Study Groups criteria. GDM prevalence ranged from 15.5% (2012) to 19.9% (2017). Increasing age was associated with GDM; women aged >40 years versus those aged >25 years had an adjusted odds ratio (OR) of 5.91 (95% confidence interval [CI] 4.202–8.314). A positive correlation was observed between weight and GDM risk; obese women versus normal‐weight women had an adjusted OR of 2.508 (95% CI 2.253–2.792). Family history of diabetes and hypertension were more commonly observed among women with GDM. Multivariate analysis showed that family history of diabetes (OR 1.101, 90% CI 1.028–1.180), weight gain during early pregnancy (OR 1.087, 90% CI 1.052–1.124) and systolic blood pressure (OR 1.015, 90% CI 1.011–1.020) were risk factors associated with GDM incidence. CONCLUSIONS: GDM affects 17.6% of all pregnant women in Xiamen. Age and maternal obesity were major contributors to GDM. The trend of GDM risk remained stable during the study. John Wiley and Sons Inc. 2019-04-11 2019-09 /pmc/articles/PMC6717898/ /pubmed/30869198 http://dx.doi.org/10.1111/jdi.13039 Text en © 2019 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Articles
Yan, Bing
Yu, Yaxin
Lin, Mingzhu
Li, Zhibin
Wang, Liying
Huang, Peiying
Song, Haiqu
Shi, Xiulin
Yang, Shuyu
Li, Xiaoying
Li, Xuejun
High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China
title High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China
title_full High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China
title_fullStr High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China
title_full_unstemmed High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China
title_short High, but stable, trend in the prevalence of gestational diabetes mellitus: A population‐based study in Xiamen, China
title_sort high, but stable, trend in the prevalence of gestational diabetes mellitus: a population‐based study in xiamen, china
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717898/
https://www.ncbi.nlm.nih.gov/pubmed/30869198
http://dx.doi.org/10.1111/jdi.13039
work_keys_str_mv AT yanbing highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT yuyaxin highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT linmingzhu highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT lizhibin highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT wangliying highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT huangpeiying highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT songhaiqu highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT shixiulin highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT yangshuyu highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT lixiaoying highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina
AT lixuejun highbutstabletrendintheprevalenceofgestationaldiabetesmellitusapopulationbasedstudyinxiamenchina