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Adverse reaction regarding titanium-based marker clip: case report of a potential complication

Adverse reaction to titanium-based breast marker clip is a very uncommon complication in medicine. We report a 65-year-old female patient who was referred with left breast lumpiness to the assessment clinic. Breast radiology with interesting sequelae following titanium clip insertion, in combination...

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Autores principales: Wegner, Urszula, Rainford, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718166/
https://www.ncbi.nlm.nih.gov/pubmed/31695515
http://dx.doi.org/10.2147/IMCRJ.S222484
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author Wegner, Urszula
Rainford, Sarah
author_facet Wegner, Urszula
Rainford, Sarah
author_sort Wegner, Urszula
collection PubMed
description Adverse reaction to titanium-based breast marker clip is a very uncommon complication in medicine. We report a 65-year-old female patient who was referred with left breast lumpiness to the assessment clinic. Breast radiology with interesting sequelae following titanium clip insertion, in combination with literature review, will be discussed. The patient had a history of adverse skin reactions to base metals. However, no allergy specifically to titanium was reported. Imaging findings with regard to the symptomatic breast were nonspecific; thus, multiple core biopsies were taken, and titanium clip was inserted. Subsequent histological examination showed benign changes. However, 7 weeks later, the marked area became very tender and the same patient re-presented to the clinic, requesting removal of the metallic component. Following multidisciplinary meetings and discussions, the person underwent ultrasound-guided vacuum biopsy and the clip was removed. The symptoms completely resolved after the successful procedure, and histological examination revealed lymphocytic infiltration of the tissues. Reactions to titanium-based marker clips are rare and only limited records have been found in the literature. More cases need to be reported in order to establish the full significance of such adverse sequelae. It is recommended that medical history with regard to allergies, prior titanium clip insertions, should be discussed.
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spelling pubmed-67181662019-11-06 Adverse reaction regarding titanium-based marker clip: case report of a potential complication Wegner, Urszula Rainford, Sarah Int Med Case Rep J Case Report Adverse reaction to titanium-based breast marker clip is a very uncommon complication in medicine. We report a 65-year-old female patient who was referred with left breast lumpiness to the assessment clinic. Breast radiology with interesting sequelae following titanium clip insertion, in combination with literature review, will be discussed. The patient had a history of adverse skin reactions to base metals. However, no allergy specifically to titanium was reported. Imaging findings with regard to the symptomatic breast were nonspecific; thus, multiple core biopsies were taken, and titanium clip was inserted. Subsequent histological examination showed benign changes. However, 7 weeks later, the marked area became very tender and the same patient re-presented to the clinic, requesting removal of the metallic component. Following multidisciplinary meetings and discussions, the person underwent ultrasound-guided vacuum biopsy and the clip was removed. The symptoms completely resolved after the successful procedure, and histological examination revealed lymphocytic infiltration of the tissues. Reactions to titanium-based marker clips are rare and only limited records have been found in the literature. More cases need to be reported in order to establish the full significance of such adverse sequelae. It is recommended that medical history with regard to allergies, prior titanium clip insertions, should be discussed. Dove 2019-08-28 /pmc/articles/PMC6718166/ /pubmed/31695515 http://dx.doi.org/10.2147/IMCRJ.S222484 Text en © 2019 Wegner and Rainford. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Wegner, Urszula
Rainford, Sarah
Adverse reaction regarding titanium-based marker clip: case report of a potential complication
title Adverse reaction regarding titanium-based marker clip: case report of a potential complication
title_full Adverse reaction regarding titanium-based marker clip: case report of a potential complication
title_fullStr Adverse reaction regarding titanium-based marker clip: case report of a potential complication
title_full_unstemmed Adverse reaction regarding titanium-based marker clip: case report of a potential complication
title_short Adverse reaction regarding titanium-based marker clip: case report of a potential complication
title_sort adverse reaction regarding titanium-based marker clip: case report of a potential complication
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718166/
https://www.ncbi.nlm.nih.gov/pubmed/31695515
http://dx.doi.org/10.2147/IMCRJ.S222484
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