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Innate immunity limits protective adaptive immune responses against pre-erythrocytic malaria parasites

Immunization with attenuated whole Plasmodium sporozoites constitutes a promising vaccination strategy. Compared to replication-deficient parasites, immunization with replication-competent parasites confers better protection and also induces a type I IFN (IFN-1) response, but whether this IFN-1 resp...

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Detalles Bibliográficos
Autores principales:	Minkah, Nana K., Wilder, Brandon K., Sheikh, Amina A., Martinson, Thomas, Wegmair, Lisa, Vaughan, Ashley M., Kappe, Stefan H. I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718385/ https://www.ncbi.nlm.nih.gov/pubmed/31477704 http://dx.doi.org/10.1038/s41467-019-11819-0

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