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Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy

Resistant tumours are thought to arise from the action of Darwinian selection on genetically heterogenous cancer cell populations. However, simple clonal selection is inadequate to describe the late relapses often characterising luminal breast cancers treated with endocrine therapy (ET), suggesting...

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Detalles Bibliográficos
Autores principales:	Hong, Sung Pil, Chan, Thalia E., Lombardo, Ylenia, Corleone, Giacomo, Rotmensz, Nicole, Bravaccini, Sara, Rocca, Andrea, Pruneri, Giancarlo, McEwen, Kirsten R., Coombes, R. Charles, Barozzi, Iros, Magnani, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718416/ https://www.ncbi.nlm.nih.gov/pubmed/31477698 http://dx.doi.org/10.1038/s41467-019-11721-9

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