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IL-23/IL-17 Axis Activates IL-1β-Associated Inflammasome in Macrophages and Generates an Auto-Inflammatory Response in a Subgroup of Patients With Bullous Pemphigoid
Bullous Pemphigoid (BP) is a skin autoimmune blistering disease characterized by immune-mediated degradation of the dermo-epidermal junction and release of a large number of inflammatory cytokines. Interleukin-1β (IL-1β) is a pleiotropic pro-inflammatory cytokine associated with inflammasome activat...
Autores principales: | Le Jan, Sébastien, Muller, Céline, Plee, Julie, Durlach, Anne, Bernard, Philippe, Antonicelli, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718471/ https://www.ncbi.nlm.nih.gov/pubmed/31507596 http://dx.doi.org/10.3389/fimmu.2019.01972 |
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