Forkhead box O3 protects the heart against paraquat‐induced aging‐associated phenotypes by upregulating the expression of antioxidant enzymes

Paraquat (PQ) promotes cell senescence in brain tissue, which contributes to Parkinson's disease. Furthermore, PQ induces heart failure and oxidative damage, but it remains unknown whether and how PQ induces cardiac aging. Here, we demonstrate that PQ induces phenotypes associated with senescen...

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Detalles Bibliográficos
Autores principales: Chang, Zao‐Shang, Xia, Jing‐Bo, Wu, Hai‐Yan, Peng, Wen‐Tao, Jiang, Fu‐Qing, Li, Jing, Liang, Chi‐Qian, Zhao, Hui, Park, Kyu‐Sang, Song, Guo‐Hua, Kim, Soo‐Ki, Huang, Ruijin, Zheng, Li, Cai, Dong‐Qing, Qi, Xu‐Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718552/
https://www.ncbi.nlm.nih.gov/pubmed/31264342
http://dx.doi.org/10.1111/acel.12990

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