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PGC‐1a integrates a metabolism and growth network linked to caloric restriction
Deleterious changes in energy metabolism have been linked to aging and disease vulnerability, while activation of mitochondrial pathways has been linked to delayed aging by caloric restriction (CR). The basis for these associations is poorly understood, and the scope of impact of mitochondrial activ...
Autores principales: | Miller, Karl N., Clark, Josef P., Martin, Stephen A., Howell, Porsha R., Burhans, Maggie S., Haws, Spencer A., Johnson, Nathan B., Rhoads, Timothy W, Pavelec, Derek M., Eliceiri, Kevin W., Roopra, Avtar S., Ntambi, James M., Denu, John M., Parks, Brian W., Anderson, Rozalyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718593/ https://www.ncbi.nlm.nih.gov/pubmed/31267675 http://dx.doi.org/10.1111/acel.12999 |
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