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Genome-wide profiling of DNA methylome and transcriptome in peripheral blood monocytes for major depression: A Monozygotic Discordant Twin Study

DNA methylation plays an important role in major depressive disorder (MDD), but the specific genes and genomic regions associated with MDD remain largely unknown. Here we conducted genome-wide profiling of DNA methylation (Infinium MethylationEPIC BeadChip) and gene expression (RNA-seq) in periphera...

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Detalles Bibliográficos
Autores principales: Zhu, Yun, Strachan, Eric, Fowler, Emily, Bacus, Tamara, Roy-Byrne, Peter, Zhao, Jinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718674/
https://www.ncbi.nlm.nih.gov/pubmed/31477685
http://dx.doi.org/10.1038/s41398-019-0550-2