Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study

CYP enzyme induction is a sensitive biomarker for phenotypic metabolic competence of in vitro test systems; it is a key event associated with thyroid disruption, and a biomarker for toxicologically relevant nuclear receptor-mediated pathways. This paper summarises the results of a multi-laboratory v...

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Detalles Bibliográficos
Autores principales: Bernasconi, Camilla, Pelkonen, Olavi, Andersson, Tommy B., Strickland, Judy, Wilk-Zasadna, Iwona, Asturiol, David, Cole, Thomas, Liska, Roman, Worth, Andrew, Müller-Vieira, Ursula, Richert, Lysiane, Chesne, Christophe, Coecke, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718736/
https://www.ncbi.nlm.nih.gov/pubmed/31158489
http://dx.doi.org/10.1016/j.tiv.2019.05.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718736/
https://www.ncbi.nlm.nih.gov/pubmed/31158489
http://dx.doi.org/10.1016/j.tiv.2019.05.019

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