RNA-Binding Protein HuR Regulates Rac1 Nucleocytoplasmic Shuttling Through Nucleophosmin in the Intestinal Epithelium

BACKGROUND & AIMS: The mammalian intestinal epithelium is a rapidly self-renewing tissue in the body, and its homeostasis is tightly regulated via well-controlled mechanisms. The RNA-binding protein HuR is essential for maintaining gut epithelial integrity, and targeted deletion of HuR in intest...

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Detalles Bibliográficos
Autores principales: Liu, Lan, Xiao, Lan, Chung, Hee K., Kwon, Min S., Li, Xiao-Xue, Wu, Na, Rao, Jaladanki N., Wang, Jian-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718926/
https://www.ncbi.nlm.nih.gov/pubmed/31195150
http://dx.doi.org/10.1016/j.jcmgh.2019.06.002

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