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Regulation of Hedgehog signaling Offers A Novel Perspective for Bone Homeostasis Disorder Treatment

The hedgehog (HH) signaling pathway is central to the regulation of bone development and homeostasis. HH signaling is not only involved in osteoblast differentiation from bone marrow mesenchymal stem cells (BM-MSCs), but also acts upstream within osteoblasts via the OPG/RANK/RANKL axis to control th...

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Detalles Bibliográficos
Autores principales: Lv, Wen-Ting, Du, Dong-Hua, Gao, Rui-Juan, Yu, Chun-Wei, Jia, Yan, Jia, Zhi-Feng, Wang, Chun-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719140/
https://www.ncbi.nlm.nih.gov/pubmed/31426273
http://dx.doi.org/10.3390/ijms20163981