Inhibition of CpLIP2 Lipase Hydrolytic Activity by Four Flavonols (Galangin, Kaempferol, Quercetin, Myricetin) Compared to Orlistat and Their Binding Mechanisms Studied by Quenching of Fluorescence

The inhibition of recombinant CpLIP2 lipase/acyltransferase from Candida parapsiolosis was considered a key model for novel antifungal drug discovery and a potential therapeutic target for candidiasis. Lipases have identified recently as potent virulence factors in C. parapsilosis and some other yea...

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Detalles Bibliográficos
Autores principales: Nasri, Ruba, Bidel, Luc P R, Rugani, Nathalie, Perrier, Véronique, Carrière, Frédéric, Dubreucq, Eric, Jay-Allemand, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719172/
https://www.ncbi.nlm.nih.gov/pubmed/31398944
http://dx.doi.org/10.3390/molecules24162888

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