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Protection of Male Rat Offspring against Hypertension Programmed by Prenatal Dexamethasone Administration and Postnatal High-Fat Diet with the Nrf2 Activator Dimethyl Fumarate during Pregnancy

Hypertension can originate from early-life exposure to oxidative stress. As reported, dimethyl fumarate (DMF) activates nuclear factor erythroid-derived 2-related factor 2 (Nrf2) and protects against oxidative stress damage. We examined whether maternal DMF therapy protects adult offspring against h...

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Detalles Bibliográficos
Autores principales: Hsu, Chien-Ning, Lin, Yu-Ju, Yu, Hong-Ren, Lin, I-Chun, Sheen, Jiunn-Ming, Huang, Li-Tung, Tain, You-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719242/
https://www.ncbi.nlm.nih.gov/pubmed/31416234
http://dx.doi.org/10.3390/ijms20163957