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Next generation sequencing based assessment of the alloreactive T cell receptor repertoire in kidney transplant patients during rejection: a prospective cohort study

BACKGROUND: Kidney transplantation is the optimal treatment in end stage renal disease but the allograft survival is still hampered by immune reactions against the allograft. This process is driven by the recognition of allogenic antigens presented to T-cells and their unique T-cell receptor (TCR) v...

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Detalles Bibliográficos
Autores principales: Aschauer, Constantin, Jelencsics, Kira, Hu, Karin, Heinzel, Andreas, Vetter, Julia, Fraunhofer, Thomas, Schaller, Susanne, Winkler, Stephan, Pimenov, Lisabeth, Gualdoni, Guido A., Eder, Michael, Kainz, Alexander, Regele, Heinz, Reindl-Schwaighofer, Roman, Oberbauer, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719356/
https://www.ncbi.nlm.nih.gov/pubmed/31477052
http://dx.doi.org/10.1186/s12882-019-1541-5