Cargando…

Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca(2+) release

Somatostatin secretion from pancreatic islet δ-cells is stimulated by elevated glucose levels, but the underlying mechanisms have only partially been elucidated. Here we show that glucose-induced somatostatin secretion (GISS) involves both membrane potential-dependent and -independent pathways. Alth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Denwood, Geoffrey, Tarasov, Andrei, Salehi, Albert, Vergari, Elisa, Ramracheya, Reshma, Takahashi, Harumi, Nikolaev, Viacheslav O., Seino, Susumo, Gribble, Fiona, Reimann, Frank, Rorsman, Patrik, Zhang, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719402/ https://www.ncbi.nlm.nih.gov/pubmed/31358556 http://dx.doi.org/10.1085/jgp.201912351

Ejemplares similares

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion
por: Vergari, Elisa, et al.
Publicado: (2019)

Somatostatin secretion by Na(+)-dependent Ca(2+)-induced Ca(2+) release in pancreatic delta-cells
por: Vergari, Elisa, et al.
Publicado: (2020)

Imaging alterations of cardiomyocyte cAMP microdomains in disease
por: Froese, Alexander, et al.
Publicado: (2015)

Regulation of colonic apical potassium (BK) channels by cAMP and somatostatin
por: Perry, M. D., et al.
Publicado: (2009)

Biophysical Techniques for Detection of cAMP and cGMP in Living Cells
por: Sprenger, Julia U., et al.
Publicado: (2013)

Monitoring real-time hormone release kinetics via high-content 3-D imaging of compensatory endocytosis
por: Tarasov, Andrei I., et al.
Publicado: (2018)

Cyclic AMP links glucose stimulation to somatostatin secretion in δ-cells
por: Tengholm, Anders
Publicado: (2019)

Mechanisms Restricting Diffusion of Intracellular cAMP
por: Agarwal, Shailesh R., et al.
Publicado: (2016)

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion
por: Gheni, Ghupurjan, et al.
Publicado: (2014)

PACmn for improved optogenetic control of intracellular cAMP
por: Yang, Shang, et al.
Publicado: (2021)

Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes
por: Pavlaki, Nikoleta, et al.
Publicado: (2018)

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells
por: Eliasson, Lena, et al.
Publicado: (2003)

Role of Membrane Microdomains in Compartmentation of cAMP Signaling
por: Agarwal, Shailesh R., et al.
Publicado: (2014)

Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis
por: Sumara, Grzegorz, et al.
Publicado: (2009)

Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains
por: Pavlaki, Nikoleta, et al.
Publicado: (2021)

Glucagon secretion from pancreatic α-cells
por: Briant, Linford, et al.
Publicado: (2016)

Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca(2+) and cAMP
por: Tolhurst, Gwen, et al.
Publicado: (2011)

Role of K(ATP) Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes
por: Zhang, Quan, et al.
Publicado: (2013)

Editorial: Frontiers in the Pharmacological Manipulation of Intracellular cAMP Levels
por: Baillie, George S., et al.
Publicado: (2016)

Can intracellular cAMP dynamics enable scalable computation?
por: Iyengar, Ravi
Publicado: (2015)

Monitoring Cannabinoid CB2 -Receptor Mediated cAMP Dynamics by FRET-Based Live Cell Imaging
por: Mensching, Leonore, et al.
Publicado: (2020)

Na(+) current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression
por: Zhang, Quan, et al.
Publicado: (2014)

GPR52 regulates cAMP in T cells but is dispensable for encephalitogenic responses
por: Krieg, Paula F., et al.
Publicado: (2023)

δ‐cells and β‐cells are electrically coupled and regulate α‐cell activity via somatostatin
por: Briant, L. J. B., et al.
Publicado: (2017)

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors
por: Calebiro, Davide, et al.
Publicado: (2009)

Functional Significance of the Adcy10-Dependent Intracellular cAMP Compartments
por: Pozdniakova, Sofya, et al.
Publicado: (2018)

Intracellular compartmentation of cAMP promotes neuroprotection and regeneration of CNS neurons
por: Cameron, Evan G., et al.
Publicado: (2017)

Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β(2)AR-cAMP Responsiveness in Murine Hearts
por: Wright, Peter T., et al.
Publicado: (2018)

Modulation of cGMP/cAMP crosstalk on the level of PDE3 in animals lacking NO-sensitive guanylyl cyclase
por: Friebe, Andreas, et al.
Publicado: (2015)

Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET
por: Sprenger, Julia U., et al.
Publicado: (2016)

Imaging cytoplasmic cAMP in mouse brainstem neurons
por: Mironov, SL, et al.
Publicado: (2009)

γ-Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic β-Cells
por: Braun, Matthias, et al.
Publicado: (2010)

Intracellular calcium and cAMP regulate directional pigment movements in teleost erythrophores
Publicado: (1994)

cAMP-mediated inhibition of intracellular particle movement and actin reorganization in Dictyostelium
Publicado: (1989)

Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes
por: Richards, Mark, et al.
Publicado: (2016)

Teasaponin suppresses Candida albicans filamentation by reducing the level of intracellular cAMP
por: Li, Ying, et al.
Publicado: (2020)

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose
por: Brereton, Melissa F., et al.
Publicado: (2014)

A K(ATP) Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans
por: MacDonald, Patrick E, et al.
Publicado: (2007)

Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β(1) and β(3)-adrenoceptor signalling
por: Kannabiran, Sukanya Arcot, et al.
Publicado: (2020)

Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4
por: Perera, Ruwan K., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_k9vmlm6esgc544dgraeh6slk0q