The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium

The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse h...

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Detalles Bibliográficos
Autores principales: Satterlee, John S., Chadwick, Lisa H., Tyson, Frederick L., McAllister, Kim, Beaver, Jill, Birnbaum, Linda, Volkow, Nora D., Wilder, Elizabeth L., Anderson, James M., Roy, Ananda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719411/
https://www.ncbi.nlm.nih.gov/pubmed/31501771
http://dx.doi.org/10.1126/sciadv.aaw6507
Descripción
Sumario:The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort.

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