Cargando…
The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium
The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse h...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719411/ https://www.ncbi.nlm.nih.gov/pubmed/31501771 http://dx.doi.org/10.1126/sciadv.aaw6507 |
_version_ | 1783447928261574656 |
---|---|
author | Satterlee, John S. Chadwick, Lisa H. Tyson, Frederick L. McAllister, Kim Beaver, Jill Birnbaum, Linda Volkow, Nora D. Wilder, Elizabeth L. Anderson, James M. Roy, Ananda L. |
author_facet | Satterlee, John S. Chadwick, Lisa H. Tyson, Frederick L. McAllister, Kim Beaver, Jill Birnbaum, Linda Volkow, Nora D. Wilder, Elizabeth L. Anderson, James M. Roy, Ananda L. |
author_sort | Satterlee, John S. |
collection | PubMed |
description | The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort. |
format | Online Article Text |
id | pubmed-6719411 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-67194112019-09-09 The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium Satterlee, John S. Chadwick, Lisa H. Tyson, Frederick L. McAllister, Kim Beaver, Jill Birnbaum, Linda Volkow, Nora D. Wilder, Elizabeth L. Anderson, James M. Roy, Ananda L. Sci Adv Reviews The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort. American Association for the Advancement of Science 2019-07-10 /pmc/articles/PMC6719411/ /pubmed/31501771 http://dx.doi.org/10.1126/sciadv.aaw6507 Text en Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Reviews Satterlee, John S. Chadwick, Lisa H. Tyson, Frederick L. McAllister, Kim Beaver, Jill Birnbaum, Linda Volkow, Nora D. Wilder, Elizabeth L. Anderson, James M. Roy, Ananda L. The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium |
title | The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium |
title_full | The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium |
title_fullStr | The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium |
title_full_unstemmed | The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium |
title_short | The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium |
title_sort | nih common fund/roadmap epigenomics program: successes of a comprehensive consortium |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719411/ https://www.ncbi.nlm.nih.gov/pubmed/31501771 http://dx.doi.org/10.1126/sciadv.aaw6507 |
work_keys_str_mv | AT satterleejohns thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT chadwicklisah thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT tysonfrederickl thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT mcallisterkim thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT beaverjill thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT birnbaumlinda thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT volkownorad thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT wilderelizabethl thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT andersonjamesm thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT royanandal thenihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT satterleejohns nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT chadwicklisah nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT tysonfrederickl nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT mcallisterkim nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT beaverjill nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT birnbaumlinda nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT volkownorad nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT wilderelizabethl nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT andersonjamesm nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium AT royanandal nihcommonfundroadmapepigenomicsprogramsuccessesofacomprehensiveconsortium |