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The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF

The ubiquitin-editing enzyme A20 is a well-known regulator of immune cell function and homeostasis. In addition, A20 protects cells from death in an ill-defined manner. While most studies focus on its role in the TNF-receptor complex, we here identify a novel component in the A20-mediated decision b...

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Detalles Bibliográficos
Autores principales:	Vetters, Jessica, van Helden, Mary J., Wahlen, Sigrid, Tavernier, Simon J., Martens, Arne, Fayazpour, Farzaneh, Vergote, Karl, Vanheerswynghels, Manon, Deswarte, Kim, Van Moorleghem, Justine, De Prijck, Sofie, Takahashi, Nozomi, Vandenabeele, Peter, Boon, Louis, van Loo, Geert, Vivier, Eric, Lambrecht, Bart N., Janssens, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719426/ https://www.ncbi.nlm.nih.gov/pubmed/31296735 http://dx.doi.org/10.1084/jem.20182164

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