Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs

We have identified a precursor that differentiates into granulocytes in vitro and in vivo yet belongs to the monocytic lineage. We have termed these cells monocyte-like precursors of granulocytes (MLPGs). Under steady state conditions, MLPGs were absent in the spleen and barely detectable in the bon...

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Detalles Bibliográficos
Autores principales: Mastio, Jérôme, Condamine, Thomas, Dominguez, George, Kossenkov, Andrew V., Donthireddy, Laxminarasimha, Veglia, Filippo, Lin, Cindy, Wang, Fang, Fu, Shuyu, Zhou, Jie, Viatour, Patrick, Lavilla-Alonso, Sergio, Polo, Alexander T., Tcyganov, Evgenii N., Mulligan, Charles, Nam, Brian, Bennett, Joseph, Masters, Gregory, Guarino, Michael, Kumar, Amit, Nefedova, Yulia, Vonderheide, Robert H., Languino, Lucia R., Abrams, Scott I., Gabrilovich, Dmitry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719429/
https://www.ncbi.nlm.nih.gov/pubmed/31239386
http://dx.doi.org/10.1084/jem.20181952

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