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Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth

Regulated growth plate activity is essential for postnatal bone development and body stature, yet the systems regulating epiphyseal fusion are poorly understood. Here, we show that the tissue inhibitors of metalloprotease (TIMP) gene family is essential for normal bone growth after birth. Whole-body...

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Detalles Bibliográficos
Autores principales:	Saw, Sanjay, Aiken, Alison, Fang, Hui, McKee, Trevor D., Bregant, Sarah, Sanchez, Otto, Chen, Yan, Weiss, Ashley, Dickson, Brendan C., Czarny, Bertrand, Sinha, Ankit, Fosang, Amanda, Dive, Vincent, Waterhouse, Paul D., Kislinger, Thomas, Khokha, Rama
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719459/ https://www.ncbi.nlm.nih.gov/pubmed/31371388 http://dx.doi.org/10.1083/jcb.201906059

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