Microtubule minus-end stability is dictated by the tubulin off-rate

Dynamic organization of microtubule minus ends is vital for the formation and maintenance of acentrosomal microtubule arrays. In vitro, both microtubule ends switch between phases of assembly and disassembly, a behavior called dynamic instability. Although minus ends grow slower, their lifetimes are...

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Detalles Bibliográficos
Autores principales: Strothman, Claire, Farmer, Veronica, Arpağ, Göker, Rodgers, Nicole, Podolski, Marija, Norris, Stephen, Ohi, Ryoma, Zanic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719460/
https://www.ncbi.nlm.nih.gov/pubmed/31420452
http://dx.doi.org/10.1083/jcb.201905019