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Programming for T-lymphocyte fates: modularity and mechanisms
T-cell development in mammals is a model for lineage choice and differentiation from multipotent stem cells. Although T-cell fate choice is promoted by signaling in the thymus through one dominant pathway, the Notch pathway, it entails a complex set of gene regulatory network and chromatin state cha...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719619/ https://www.ncbi.nlm.nih.gov/pubmed/31481536 http://dx.doi.org/10.1101/gad.327163.119 |