Cargando…

Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience

INTRODUCTION: Menopause is defined as a 12-month period of time when menstruation permanently ceases. In some cases, menopause may be caused by external factors – for example gonadotoxic treatment that irreversibly damages ovarian tissue leading to loss of its hormonal and reproductive function. Onc...

Descripción completa

Detalles Bibliográficos
Autores principales: Horbaczewska, Anna, Jach, Robert, Zmaczyński, Andrzej, Kacalska-Janssen, Olga, Doroszewska, Katarzyna, Piróg, Magdalena, Kabzińska-Turek, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719631/
https://www.ncbi.nlm.nih.gov/pubmed/31485201
http://dx.doi.org/10.5114/pm.2019.85787
_version_ 1783447965388505088
author Horbaczewska, Anna
Jach, Robert
Zmaczyński, Andrzej
Kacalska-Janssen, Olga
Doroszewska, Katarzyna
Piróg, Magdalena
Kabzińska-Turek, Monika
author_facet Horbaczewska, Anna
Jach, Robert
Zmaczyński, Andrzej
Kacalska-Janssen, Olga
Doroszewska, Katarzyna
Piróg, Magdalena
Kabzińska-Turek, Monika
author_sort Horbaczewska, Anna
collection PubMed
description INTRODUCTION: Menopause is defined as a 12-month period of time when menstruation permanently ceases. In some cases, menopause may be caused by external factors – for example gonadotoxic treatment that irreversibly damages ovarian tissue leading to loss of its hormonal and reproductive function. Oncofertility is a discipline that merges oncology and reproductive medicine, giving patients a chance to experience parenthood after gonadotoxic treatment is finished. AIM OF THE STUDY: The purpose of the study is to present the implementation and first outcomes of the Oncofertility Programme in the University Clinic of Endocrinological Gynaecology and Gynaecology, University Hospital in Krakow, Poland. MATERIAL AND METHODS: Patients interested in fertility preservation have been consulted in the University Clinic of Endocrinological Gynaecology and Gynaecology in Krakow since April 2016. Preliminary qualification to one of the available methods (embryo cryopreservation, oocyte cryopreservation, ovarian tissue cryopreservation) was conducted. Patients declaring a wish to join the programme were then referred to one of the three infertility treatment centres cooperating with the University Clinic, in order to undergo the chosen procedure. RESULTS: During a period of 24 months, 18 patients were consulted. The youngest consulted patient was 20 years old, the oldest 39. Two years after the first consultation, a telephone survey among consulted patients was carried out to verify whether the patients finally underwent oncofertility procedures, and to ask about their reproductive status. CONCLUSIONS: The problem of fertility issues being inadequately addressed results in low referral rates to oncofertility programmes. Attempts to raise awareness of oncofertility possibilities among oncologists should be undertaken because critically few patients are being referred to oncofertility centres.
format Online
Article
Text
id pubmed-6719631
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-67196312019-09-04 Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience Horbaczewska, Anna Jach, Robert Zmaczyński, Andrzej Kacalska-Janssen, Olga Doroszewska, Katarzyna Piróg, Magdalena Kabzińska-Turek, Monika Prz Menopauzalny Original Paper INTRODUCTION: Menopause is defined as a 12-month period of time when menstruation permanently ceases. In some cases, menopause may be caused by external factors – for example gonadotoxic treatment that irreversibly damages ovarian tissue leading to loss of its hormonal and reproductive function. Oncofertility is a discipline that merges oncology and reproductive medicine, giving patients a chance to experience parenthood after gonadotoxic treatment is finished. AIM OF THE STUDY: The purpose of the study is to present the implementation and first outcomes of the Oncofertility Programme in the University Clinic of Endocrinological Gynaecology and Gynaecology, University Hospital in Krakow, Poland. MATERIAL AND METHODS: Patients interested in fertility preservation have been consulted in the University Clinic of Endocrinological Gynaecology and Gynaecology in Krakow since April 2016. Preliminary qualification to one of the available methods (embryo cryopreservation, oocyte cryopreservation, ovarian tissue cryopreservation) was conducted. Patients declaring a wish to join the programme were then referred to one of the three infertility treatment centres cooperating with the University Clinic, in order to undergo the chosen procedure. RESULTS: During a period of 24 months, 18 patients were consulted. The youngest consulted patient was 20 years old, the oldest 39. Two years after the first consultation, a telephone survey among consulted patients was carried out to verify whether the patients finally underwent oncofertility procedures, and to ask about their reproductive status. CONCLUSIONS: The problem of fertility issues being inadequately addressed results in low referral rates to oncofertility programmes. Attempts to raise awareness of oncofertility possibilities among oncologists should be undertaken because critically few patients are being referred to oncofertility centres. Termedia Publishing House 2019-06-14 2019-06 /pmc/articles/PMC6719631/ /pubmed/31485201 http://dx.doi.org/10.5114/pm.2019.85787 Text en Copyright: © 2019 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Horbaczewska, Anna
Jach, Robert
Zmaczyński, Andrzej
Kacalska-Janssen, Olga
Doroszewska, Katarzyna
Piróg, Magdalena
Kabzińska-Turek, Monika
Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience
title Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience
title_full Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience
title_fullStr Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience
title_full_unstemmed Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience
title_short Challenging iatrogenic menopause. Oncofertility programme in Poland – a single-centre experience
title_sort challenging iatrogenic menopause. oncofertility programme in poland – a single-centre experience
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719631/
https://www.ncbi.nlm.nih.gov/pubmed/31485201
http://dx.doi.org/10.5114/pm.2019.85787
work_keys_str_mv AT horbaczewskaanna challengingiatrogenicmenopauseoncofertilityprogrammeinpolandasinglecentreexperience
AT jachrobert challengingiatrogenicmenopauseoncofertilityprogrammeinpolandasinglecentreexperience
AT zmaczynskiandrzej challengingiatrogenicmenopauseoncofertilityprogrammeinpolandasinglecentreexperience
AT kacalskajanssenolga challengingiatrogenicmenopauseoncofertilityprogrammeinpolandasinglecentreexperience
AT doroszewskakatarzyna challengingiatrogenicmenopauseoncofertilityprogrammeinpolandasinglecentreexperience
AT pirogmagdalena challengingiatrogenicmenopauseoncofertilityprogrammeinpolandasinglecentreexperience
AT kabzinskaturekmonika challengingiatrogenicmenopauseoncofertilityprogrammeinpolandasinglecentreexperience