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Single-cell analysis of cardiogenesis reveals basis for organ level developmental defects
Organogenesis involves integration of myriad cell types, and dysregulation of cellular gene networks results in birth defects, affecting 5 per cent of live births. Congenital heart defects (CHD) are the most common malformations and result from disruption of discrete subsets of cardiac progenitor ce...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719697/ https://www.ncbi.nlm.nih.gov/pubmed/31341279 http://dx.doi.org/10.1038/s41586-019-1414-x |