Cargando…
TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8(+) T-cell homeostasis
Dendritic cells (DCs) play pivotal roles in T-cell homeostasis and activation, and metabolic programing has been recently linked to DC development and function. However, the metabolic underpinnings corresponding to distinct DC functions remain largely unresolved. Here, we demonstrate a special metab...
Autores principales: | Shi, Lei, Chen, Xia, Zang, Aiping, Li, Tiantian, Hu, Yanxiang, Ma, Shixin, Lü, Mengdie, Yin, Huiyong, Wang, Haikun, Zhang, Xiaoming, Zhang, Bei, Leng, Qibin, Yang, Jinbo, Xiao, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719877/ https://www.ncbi.nlm.nih.gov/pubmed/31433805 http://dx.doi.org/10.1371/journal.pbio.3000420 |
Ejemplares similares
-
The TSC-mTOR pathway regulates macrophage polarization
por: Byles, Vanessa, et al.
Publicado: (2013) -
TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway
por: Jin, Shan, et al.
Publicado: (2018) -
Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway
por: Presneau, N, et al.
Publicado: (2009) -
Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer
por: Mrozek, Evelyn M., et al.
Publicado: (2021) -
Is mTOR Inhibitor Good Enough for Treatment All Tumors in TSC Patients?
por: Habib, Samy L, et al.
Publicado: (2016)