Astroglial dysfunctions drive aberrant synaptogenesis and social behavioral deficits in mice with neonatal exposure to lengthy general anesthesia

Lengthy use of general anesthetics (GAs) causes neurobehavioral deficits in the developing brain, which has raised significant clinical concerns such that the United States Food and Drug Administration (FDA) is warning on the use of GAs in children younger than 3 years. However, the molecular and ce...

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Detalles Bibliográficos
Autores principales: Zhou, Bin, Chen, Lingmin, Liao, Ping, Huang, Lu, Chen, Zhuo, Liao, Daqing, Yang, Linghui, Wang, Jing, Yu, Guoqiang, Wang, Li, Zhang, Jianguo, Zuo, Yunxia, Liu, Jin, Jiang, Ruotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719896/
https://www.ncbi.nlm.nih.gov/pubmed/31433818
http://dx.doi.org/10.1371/journal.pbio.3000086

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