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Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study

Cardiovascular diseases are one of most frequent cause of morbidity and mortality in the world. There is an emerging need for integrated, non-invasive, and easy-to-use clinical tools to assess accurately cardiovascular system primarily in the preventative medicine. We present a novel design for a no...

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Autores principales: Fabian, Vratislav, Matera, Lukas, Bayerova, Kristyna, Havlik, Jan, Kremen, Vaclav, Pudil, Jan, Sajgalik, Pavol, Zemanek, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719951/
https://www.ncbi.nlm.nih.gov/pubmed/31398931
http://dx.doi.org/10.3390/s19163467
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author Fabian, Vratislav
Matera, Lukas
Bayerova, Kristyna
Havlik, Jan
Kremen, Vaclav
Pudil, Jan
Sajgalik, Pavol
Zemanek, David
author_facet Fabian, Vratislav
Matera, Lukas
Bayerova, Kristyna
Havlik, Jan
Kremen, Vaclav
Pudil, Jan
Sajgalik, Pavol
Zemanek, David
author_sort Fabian, Vratislav
collection PubMed
description Cardiovascular diseases are one of most frequent cause of morbidity and mortality in the world. There is an emerging need for integrated, non-invasive, and easy-to-use clinical tools to assess accurately cardiovascular system primarily in the preventative medicine. We present a novel design for a non-invasive pulse wave velocity (PWV) assessment method integrated in a single brachial blood pressure monitor allowing for up to 100 times more sensitive recording of the pressure pulsations based on a brachial occlusion-cuff (suprasystolic) principle. The monitor prototype with built-in proprietary method was validated with a gold standard reference technique SphygmoCor VX device. The blood pressure and PWV were assessed on twenty-five healthy individuals (9 women, age (37 ± 13) years) in a supine position at rest by a brachial cuff blood pressure monitor prototype, and immediately re-tested using a gold standard method. PWV using our BP monitor was (6.67 ± 0.96) m/s compared to PWV determined by SphygmoCor VX (6.15 ± 1.01) m/s. The correlation between methods using a Pearson’s correlation coefficient was r = 0.88 (p < 0.001). The study demonstrates the feasibility of using a single brachial cuff build-in technique for the assessment of the arterial stiffness from a single ambulatory blood pressure assessment.
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spelling pubmed-67199512019-09-10 Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study Fabian, Vratislav Matera, Lukas Bayerova, Kristyna Havlik, Jan Kremen, Vaclav Pudil, Jan Sajgalik, Pavol Zemanek, David Sensors (Basel) Article Cardiovascular diseases are one of most frequent cause of morbidity and mortality in the world. There is an emerging need for integrated, non-invasive, and easy-to-use clinical tools to assess accurately cardiovascular system primarily in the preventative medicine. We present a novel design for a non-invasive pulse wave velocity (PWV) assessment method integrated in a single brachial blood pressure monitor allowing for up to 100 times more sensitive recording of the pressure pulsations based on a brachial occlusion-cuff (suprasystolic) principle. The monitor prototype with built-in proprietary method was validated with a gold standard reference technique SphygmoCor VX device. The blood pressure and PWV were assessed on twenty-five healthy individuals (9 women, age (37 ± 13) years) in a supine position at rest by a brachial cuff blood pressure monitor prototype, and immediately re-tested using a gold standard method. PWV using our BP monitor was (6.67 ± 0.96) m/s compared to PWV determined by SphygmoCor VX (6.15 ± 1.01) m/s. The correlation between methods using a Pearson’s correlation coefficient was r = 0.88 (p < 0.001). The study demonstrates the feasibility of using a single brachial cuff build-in technique for the assessment of the arterial stiffness from a single ambulatory blood pressure assessment. MDPI 2019-08-08 /pmc/articles/PMC6719951/ /pubmed/31398931 http://dx.doi.org/10.3390/s19163467 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fabian, Vratislav
Matera, Lukas
Bayerova, Kristyna
Havlik, Jan
Kremen, Vaclav
Pudil, Jan
Sajgalik, Pavol
Zemanek, David
Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study
title Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study
title_full Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study
title_fullStr Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study
title_full_unstemmed Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study
title_short Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study
title_sort noninvasive assessment of aortic pulse wave velocity by the brachial occlusion-cuff technique: comparative study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719951/
https://www.ncbi.nlm.nih.gov/pubmed/31398931
http://dx.doi.org/10.3390/s19163467
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