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Potential for Tight Junction Protein–Directed Drug Development Using Claudin Binders and Angubindin-1

The tight junction (TJ) is an intercellular sealing component found in epithelial and endothelial tissues that regulates the passage of solutes across the paracellular space. Research examining the biology of TJs has revealed that they are complex biochemical structures constructed from a range of p...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yosuke, Tachibana, Keisuke, Krug, Susanne M., Kunisawa, Jun, Fromm, Michael, Kondoh, Masuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719960/
https://www.ncbi.nlm.nih.gov/pubmed/31426497
http://dx.doi.org/10.3390/ijms20164016