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Potential for Tight Junction Protein–Directed Drug Development Using Claudin Binders and Angubindin-1
The tight junction (TJ) is an intercellular sealing component found in epithelial and endothelial tissues that regulates the passage of solutes across the paracellular space. Research examining the biology of TJs has revealed that they are complex biochemical structures constructed from a range of p...
Autores principales: | Hashimoto, Yosuke, Tachibana, Keisuke, Krug, Susanne M., Kunisawa, Jun, Fromm, Michael, Kondoh, Masuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719960/ https://www.ncbi.nlm.nih.gov/pubmed/31426497 http://dx.doi.org/10.3390/ijms20164016 |
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