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AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway

We previously demonstrated that angiotensin-(1-7) (Ang-(1-7)), an essential endocrine factor, inhibits the NLRP3 inflammasome by regulating reactive oxygen species (ROS) in fibrotic livers. We also demonstrated that the NLRP3 inflammasome contributes to the liver damage induced by pyroptosis after h...

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Detalles Bibliográficos
Autores principales:	Zhang, Ming, Zhu, Xintao, Tong, Huasheng, Lou, Anni, Li, Yue, Li, Yang, Su, Lei, Li, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720052/ https://www.ncbi.nlm.nih.gov/pubmed/31531346 http://dx.doi.org/10.1155/2019/1806234

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