Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale

BACKGROUND: Rodent models are invaluable for studying biological processes in the context of whole organisms. The reproducibility of such research is based on an assumption of metabolic similarity between experimental animals, controlled for by breeding and housing strategies that minimise genetic a...

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Detalles Bibliográficos
Autores principales: Randall, David William, Kieswich, Julius, Swann, Jonathan, McCafferty, Kieran, Thiemermann, Christoph, Curtis, Michael, Hoyles, Lesley, Yaqoob, Muhammed Magdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720068/
https://www.ncbi.nlm.nih.gov/pubmed/31477171
http://dx.doi.org/10.1186/s40168-019-0738-y

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