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Insulin‐like growth factor binding protein‐4 exerts antifibrotic activity by reducing levels of connective tissue growth factor and the C‐X‐C chemokine receptor 4
The insulin‐like growth factor (IGF) system plays an important role in variety cellular biological functions; we previously reported levels of IGF binding proteins (IGFBP)‐3 and ‐5 are increased in dermal and pulmonary fibrosis associated with the prototypic fibrosing disease systemic sclerosis (SSc...
Autores principales: | Su, YunYun, Nishimoto, Tetsuya, Hoffman, Stanley, Nguyen, Xinh‐Xinh, Pilewski, Joseph M., Feghali‐Bostwick, Carol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720120/ https://www.ncbi.nlm.nih.gov/pubmed/31482149 http://dx.doi.org/10.1096/fba.2018-00015 |
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