A prospective study on urine alkalization with an oral regimen consisting of sodium bicarbonate and acetazolamide in patients receiving high-dose methotrexate

PURPOSE: Intravenous (IV) sodium bicarbonate is typically used in alkalization regimens for the safe use of the chemotherapeutic agent high-dose methotrexate (HDMTX). Urine parameters including urine output and pH are important in order to minimize the risk of kidney injury, which increases adverse...

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Detalles Bibliográficos
Autores principales: Reed, Daniel R, Pierce, Eric J, Sen, Jeremy M, Keng, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720153/
https://www.ncbi.nlm.nih.gov/pubmed/31507329
http://dx.doi.org/10.2147/CMAR.S190084

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