H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer

Estrogen and hypoxia promote an aggressive phenotype in prostate cancer (PCa), driving transcription of progression-associated genes. Here, we molecularly dissect the contribution of long non-coding RNA H19 to PCa metastatic potential under combined stimuli, a topic largely uncovered. The effects of...

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Detalles Bibliográficos
Autores principales: Bacci, Lorenza, Aiello, Aurora, Ripoli, Cristian, Loria, Rossella, Pugliese, Dario, Pierconti, Francesco, Rotili, Dante, Strigari, Lidia, Pinto, Francesco, Bassi, Pier Francesco, Mai, Antonello, Grassi, Claudio, Pontecorvi, Alfredo, Falcioni, Rita, Farsetti, Antonella, Nanni, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720303/
https://www.ncbi.nlm.nih.gov/pubmed/31426484
http://dx.doi.org/10.3390/ijms20164012

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