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Design, synthesis, in vitro potent antiproliferative activity, and kinase inhibitory effects of new triarylpyrazole derivatives possessing different heterocycle terminal moieties

A new series of triarylpyrazole derivatives having different heterocycle terminal groups have been designed and synthesised. Compounds 1h–j and 1l exhibited the highest mean percentage inhibition against the 58 cancer cell lines at a concentration of 10 μM, and thus were next examined in 5-dose test...

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Detalles Bibliográficos
Autores principales: Gamal El-Din, Mahmoud M., El-Gamal, Mohammed I., Abdel-Maksoud, Mohammed S., Yoo, Kyung Ho, Oh, Chang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720312/
https://www.ncbi.nlm.nih.gov/pubmed/31452407
http://dx.doi.org/10.1080/14756366.2019.1653292

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