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Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016

OBJECTIVES: This study aimed to assess the association between positive roadside tests for delta-9-tetrahydrocannabinol (THC) and other driving-impairing substances and THC concentrations and the age and gender of THC-positive drivers. DESIGN: This study is based on administrative data. SETTING, PAR...

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Autores principales: Herrera-Gómez, Francisco, García-Mingo, Mercedes, Colás, Mónica, González-Luque, Juan Carlos, Alvarez, F Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720329/
https://www.ncbi.nlm.nih.gov/pubmed/31455697
http://dx.doi.org/10.1136/bmjopen-2018-026648
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author Herrera-Gómez, Francisco
García-Mingo, Mercedes
Colás, Mónica
González-Luque, Juan Carlos
Alvarez, F Javier
author_facet Herrera-Gómez, Francisco
García-Mingo, Mercedes
Colás, Mónica
González-Luque, Juan Carlos
Alvarez, F Javier
author_sort Herrera-Gómez, Francisco
collection PubMed
description OBJECTIVES: This study aimed to assess the association between positive roadside tests for delta-9-tetrahydrocannabinol (THC) and other driving-impairing substances and THC concentrations and the age and gender of THC-positive drivers. DESIGN: This study is based on administrative data. SETTING, PARTICIPANTS AND EXPOSURES: National administrative data on drivers who tested positive in confirmation analysis of driving-impairing substances in oral fluid were assessed (2011–2016, 179 645 tests). PRIMARY AND SECONDARY OUTCOME MEASURES: Frequencies of positivity for THC, THC alone and THC plus non-THC substances (stratification by age and gender in 2016) and THC concentration were obtained. Comparisons and univariate and multivariate regression analyses were performed. RESULTS: Of the 65 244 confirmed drug-positive tests, 51 869 were positive for THC (79.5%). In 50.8% of the THC-positive tests, cocaine and amphetamines were also detected. Positivity for THC and non-THC substances predominated among drivers with low THC concentrations and represented 58.6% of those with levels lower than 25 ng/mL. The mean±SD for age was 29.6±7.7 years (year 2016, n=24 941). Men accounted for 96.3% of all THC-positive drivers. With increasing age, positivity for THC decreased (OR 0.948; 95% CI 0.945 to 0.952; p<0.0001), and positivity for THC and non-THC substances increased (OR 1.021; 95% CI 1.017 to 1.024; p<0.0001). Men were associated with higher THC concentrations (OR 1.394; 95% CI 1.188 to 1.636; p<0.0001). CONCLUSIONS: Cannabis positivity is frequent among drivers, and polysubstance use is common. Hence, focusing on younger drivers and those with low THC concentrations is encouraged. This study provides evidence on the current implementation of roadside drug testing in Spain and aims to characterise driving under the influence (DUI) of cannabis to increase the awareness of all involved to help them avoid DUI.
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spelling pubmed-67203292019-09-17 Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016 Herrera-Gómez, Francisco García-Mingo, Mercedes Colás, Mónica González-Luque, Juan Carlos Alvarez, F Javier BMJ Open Addiction OBJECTIVES: This study aimed to assess the association between positive roadside tests for delta-9-tetrahydrocannabinol (THC) and other driving-impairing substances and THC concentrations and the age and gender of THC-positive drivers. DESIGN: This study is based on administrative data. SETTING, PARTICIPANTS AND EXPOSURES: National administrative data on drivers who tested positive in confirmation analysis of driving-impairing substances in oral fluid were assessed (2011–2016, 179 645 tests). PRIMARY AND SECONDARY OUTCOME MEASURES: Frequencies of positivity for THC, THC alone and THC plus non-THC substances (stratification by age and gender in 2016) and THC concentration were obtained. Comparisons and univariate and multivariate regression analyses were performed. RESULTS: Of the 65 244 confirmed drug-positive tests, 51 869 were positive for THC (79.5%). In 50.8% of the THC-positive tests, cocaine and amphetamines were also detected. Positivity for THC and non-THC substances predominated among drivers with low THC concentrations and represented 58.6% of those with levels lower than 25 ng/mL. The mean±SD for age was 29.6±7.7 years (year 2016, n=24 941). Men accounted for 96.3% of all THC-positive drivers. With increasing age, positivity for THC decreased (OR 0.948; 95% CI 0.945 to 0.952; p<0.0001), and positivity for THC and non-THC substances increased (OR 1.021; 95% CI 1.017 to 1.024; p<0.0001). Men were associated with higher THC concentrations (OR 1.394; 95% CI 1.188 to 1.636; p<0.0001). CONCLUSIONS: Cannabis positivity is frequent among drivers, and polysubstance use is common. Hence, focusing on younger drivers and those with low THC concentrations is encouraged. This study provides evidence on the current implementation of roadside drug testing in Spain and aims to characterise driving under the influence (DUI) of cannabis to increase the awareness of all involved to help them avoid DUI. BMJ Publishing Group 2019-08-26 /pmc/articles/PMC6720329/ /pubmed/31455697 http://dx.doi.org/10.1136/bmjopen-2018-026648 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Addiction
Herrera-Gómez, Francisco
García-Mingo, Mercedes
Colás, Mónica
González-Luque, Juan Carlos
Alvarez, F Javier
Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016
title Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016
title_full Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016
title_fullStr Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016
title_full_unstemmed Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016
title_short Drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for Spain between 2011 and 2016
title_sort drivers who tested positive for cannabis in oral fluid: a longitudinal analysis of administrative data for spain between 2011 and 2016
topic Addiction
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720329/
https://www.ncbi.nlm.nih.gov/pubmed/31455697
http://dx.doi.org/10.1136/bmjopen-2018-026648
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