Cargando…

Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review

Prostate cancer (PC) is the sixth most common cancer type in the world, which causes approximately 10% of total cancer fatalities. The detection of protein biomarkers in body fluids is the key topic for the diagnosis and prognosis of PC. Highly sensitive screening of PC is the most effective approac...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Li, Wen, Yanli, Pandit, Santosh, Mokkapati, Venkata R. S. S., Mijakovic, Ivan, Li, Yan, Ding, Min, Ren, Shuzhen, Li, Wen, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720397/
https://www.ncbi.nlm.nih.gov/pubmed/31508598
http://dx.doi.org/10.1186/s13065-019-0611-x
_version_ 1783448116983234560
author Xu, Li
Wen, Yanli
Pandit, Santosh
Mokkapati, Venkata R. S. S.
Mijakovic, Ivan
Li, Yan
Ding, Min
Ren, Shuzhen
Li, Wen
Liu, Gang
author_facet Xu, Li
Wen, Yanli
Pandit, Santosh
Mokkapati, Venkata R. S. S.
Mijakovic, Ivan
Li, Yan
Ding, Min
Ren, Shuzhen
Li, Wen
Liu, Gang
author_sort Xu, Li
collection PubMed
description Prostate cancer (PC) is the sixth most common cancer type in the world, which causes approximately 10% of total cancer fatalities. The detection of protein biomarkers in body fluids is the key topic for the diagnosis and prognosis of PC. Highly sensitive screening of PC is the most effective approach for reducing mortality. Thus, there are a growing number of literature that recognizes the importance of new technologies for early diagnosis of PC. Graphene is playing an important role in the biosensor field with remarkable physical, optical, electrochemical and magnetic properties. Many recent studies demonstrated the potential of graphene materials for sensitive detection of protein biomarkers. In this review, the graphene-based biosensors toward PC analysis are mainly discussed in two groups: Firstly, novel biosensor interfaces were constructed through the modification of graphene materials onto sensor surfaces. Secondly, ingenious signal amplification strategies were developed using graphene materials as catalysts or carriers. Graphene-based biosensors have exhibited remarkable performance with high sensitivities, wide detection ranges, and long-term stabilities.
format Online
Article
Text
id pubmed-6720397
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-67203972019-09-10 Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review Xu, Li Wen, Yanli Pandit, Santosh Mokkapati, Venkata R. S. S. Mijakovic, Ivan Li, Yan Ding, Min Ren, Shuzhen Li, Wen Liu, Gang BMC Chem Mini Review Prostate cancer (PC) is the sixth most common cancer type in the world, which causes approximately 10% of total cancer fatalities. The detection of protein biomarkers in body fluids is the key topic for the diagnosis and prognosis of PC. Highly sensitive screening of PC is the most effective approach for reducing mortality. Thus, there are a growing number of literature that recognizes the importance of new technologies for early diagnosis of PC. Graphene is playing an important role in the biosensor field with remarkable physical, optical, electrochemical and magnetic properties. Many recent studies demonstrated the potential of graphene materials for sensitive detection of protein biomarkers. In this review, the graphene-based biosensors toward PC analysis are mainly discussed in two groups: Firstly, novel biosensor interfaces were constructed through the modification of graphene materials onto sensor surfaces. Secondly, ingenious signal amplification strategies were developed using graphene materials as catalysts or carriers. Graphene-based biosensors have exhibited remarkable performance with high sensitivities, wide detection ranges, and long-term stabilities. Springer International Publishing 2019-09-03 /pmc/articles/PMC6720397/ /pubmed/31508598 http://dx.doi.org/10.1186/s13065-019-0611-x Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Mini Review
Xu, Li
Wen, Yanli
Pandit, Santosh
Mokkapati, Venkata R. S. S.
Mijakovic, Ivan
Li, Yan
Ding, Min
Ren, Shuzhen
Li, Wen
Liu, Gang
Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
title Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
title_full Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
title_fullStr Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
title_full_unstemmed Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
title_short Graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
title_sort graphene-based biosensors for the detection of prostate cancer protein biomarkers: a review
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720397/
https://www.ncbi.nlm.nih.gov/pubmed/31508598
http://dx.doi.org/10.1186/s13065-019-0611-x
work_keys_str_mv AT xuli graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT wenyanli graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT panditsantosh graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT mokkapativenkatarss graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT mijakovicivan graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT liyan graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT dingmin graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT renshuzhen graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT liwen graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview
AT liugang graphenebasedbiosensorsforthedetectionofprostatecancerproteinbiomarkersareview