Blockade of EGFR Activation Promotes TNF-Induced Lung Epithelial Cell Apoptosis and Pulmonary Injury

Pneumonitis is the leading cause of death associated with the use of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) against non-small cell lung cancer (NSCLC). However, the risk factors and the mechanism underlying this toxicity have not been elucidated. Tumor necrosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamaoka, Toshimitsu, Arata, Satoru, Homma, Mayumi, Homma, Tetsuya, Kusumoto, Sojiro, Ando, Koichi, Manabe, Ryou, Kishino, Yasunari, Ohba, Motoi, Tsurutani, Junji, Takimoto, Masafumi, Ohmori, Tohru, Sagara, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720446/
https://www.ncbi.nlm.nih.gov/pubmed/31426531
http://dx.doi.org/10.3390/ijms20164021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720446/
https://www.ncbi.nlm.nih.gov/pubmed/31426531
http://dx.doi.org/10.3390/ijms20164021

Ejemplares similares