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Enrichment of Short-Chain Ceramides and Free Fatty Acids in the Skin Epidermis, Liver, and Kidneys of db/db Mice, a Type 2 Diabetes Mellitus Model

Patients with diabetes mellitus (DM) often suffer from diverse skin disorders, which might be attributable to skin barrier dysfunction. To explore the role of lipid alterations in the epidermis in DM skin disorders, we quantitated 49 lipids (34 ceramides, 14 free fatty acids (FFAs), and cholesterol)...

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Detalles Bibliográficos
Autores principales: Kim, Minjeong, Jeong, Haengdueng, Lee, Buhyun, Cho, Yejin, Yoon, Won Kee, Cho, Ahreum, Kwon, Guideock, Nam, Ki Taek, Ha, Hunjoo, Lim, Kyung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720538/
https://www.ncbi.nlm.nih.gov/pubmed/30739427
http://dx.doi.org/10.4062/biomolther.2018.214

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