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Enrichment of Short-Chain Ceramides and Free Fatty Acids in the Skin Epidermis, Liver, and Kidneys of db/db Mice, a Type 2 Diabetes Mellitus Model
Patients with diabetes mellitus (DM) often suffer from diverse skin disorders, which might be attributable to skin barrier dysfunction. To explore the role of lipid alterations in the epidermis in DM skin disorders, we quantitated 49 lipids (34 ceramides, 14 free fatty acids (FFAs), and cholesterol)...
Autores principales: | Kim, Minjeong, Jeong, Haengdueng, Lee, Buhyun, Cho, Yejin, Yoon, Won Kee, Cho, Ahreum, Kwon, Guideock, Nam, Ki Taek, Ha, Hunjoo, Lim, Kyung-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720538/ https://www.ncbi.nlm.nih.gov/pubmed/30739427 http://dx.doi.org/10.4062/biomolther.2018.214 |
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