Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

Resistance to systemic drug therapy is a major reason for the failure of anticancer therapies. Here, we tested doxorubicin-loaded human serum albumin (HSA) nanoparticles in the neuroblastoma cell line UKF-NB-3 and its ABCB1-expressing sublines adapted to vincristine (UKF-NB-3(r)VCR(1)) and doxorubic...

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Detalles Bibliográficos
Autores principales: Onafuye, Hannah, Pieper, Sebastian, Mulac, Dennis, Jr., Jindrich Cinatl, Wass, Mark N, Langer, Klaus, Michaelis, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720578/
https://www.ncbi.nlm.nih.gov/pubmed/31501742
http://dx.doi.org/10.3762/bjnano.10.166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720578/
https://www.ncbi.nlm.nih.gov/pubmed/31501742
http://dx.doi.org/10.3762/bjnano.10.166

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