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Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

Resistance to systemic drug therapy is a major reason for the failure of anticancer therapies. Here, we tested doxorubicin-loaded human serum albumin (HSA) nanoparticles in the neuroblastoma cell line UKF-NB-3 and its ABCB1-expressing sublines adapted to vincristine (UKF-NB-3(r)VCR(1)) and doxorubic...

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Detalles Bibliográficos
Autores principales:	Onafuye, Hannah, Pieper, Sebastian, Mulac, Dennis, Jr., Jindrich Cinatl, Wass, Mark N, Langer, Klaus, Michaelis, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2019
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720578/ https://www.ncbi.nlm.nih.gov/pubmed/31501742 http://dx.doi.org/10.3762/bjnano.10.166

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