Cargando…

Stability Evaluation and Stabilization of a Gastrin-Releasing Peptide Receptor (GRPR) Targeting Imaging Pharmaceutical

The prostate-specific membrane antigen (PSMA) and gastrin-releasing peptide receptor (GRPR) are identified as important targets on prostate cancer. Receptor-targeting radiolabeled imaging pharmaceuticals with high affinity and specificity are useful in studying and monitoring biological processes an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghosh, Arijit, Woolum, Karen, Kothandaraman, Shankaran, Tweedle, Michael F., Kumar, Krishan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720803/ https://www.ncbi.nlm.nih.gov/pubmed/31398865 http://dx.doi.org/10.3390/molecules24162878

Ejemplares similares

The Gastrin-Releasing Peptide Receptor (GRPR) in the Spinal Cord as a Novel Pharmacological Target
por: Takanami, Keiko, et al.
Publicado: (2014)

How gastrin-releasing peptide receptor (GRPR) and α(v)β(3) integrin expression reflect reorganization features of tumors after hyperthermia treatments
por: Hallasch, Sandra, et al.
Publicado: (2017)

Preclinical Characterization of a Stabilized Gastrin-Releasing Peptide Receptor Antagonist for Targeted Cancer Theranostics
por: Abouzayed, Ayman, et al.
Publicado: (2023)

In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies
por: Chatalic, Kristell L.S., et al.
Publicado: (2016)

Novel Peptide NIRF Optical Surgical Navigation Agents for HNSCC
por: Ding, Haiming, et al.
Publicado: (2019)

Nanostrategies for Therapeutic and Diagnostic Targeting of Gastrin-Releasing Peptide Receptor
por: Rurarz, Beata Paulina, et al.
Publicado: (2023)

Radiochemistry, Production Processes, Labeling Methods, and ImmunoPET Imaging Pharmaceuticals of Iodine-124
por: Kumar, Krishan, et al.
Publicado: (2021)

Phase I Trial of [(99m)Tc]Tc-maSSS-PEG(2)-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors
por: Chernov, Vladimir, et al.
Publicado: (2023)

In Vivo Stabilized SB3, an Attractive GRPR Antagonist, for Pre- and Intra-Operative Imaging for Prostate Cancer
por: Bakker, Ingrid L., et al.
Publicado: (2018)

Positron Emission Tomography Imaging of the Gastrin-Releasing Peptide Receptor with a Novel Bombesin Analogue
por: Lau, Joseph, et al.
Publicado: (2019)

Human gastrin- releasing peptide receptor expression in women with uterine cervix cancer
por: Kunos, Charles A., et al.
Publicado: (2023)

Gastrin-Releasing Peptide and Glucose Metabolism Following Pancreatitis
por: Pendharkar, Sayali A., et al.
Publicado: (2017)

Gastrin-Releasing Peptide (GRP) Stimulates Osteoclastogenesis in Periodontitis
por: Choi, YunJeong, et al.
Publicado: (2020)

Analgesic effect of gastrin-releasing peptide in the dorsal horn
por: Saeki, Ayano, et al.
Publicado: (2022)

Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer
por: Mitran, Bogdan, et al.
Publicado: (2019)

Gastrin-releasing Peptide Receptor Imaging in Breast Cancer Using the Receptor Antagonist (68)Ga-RM2 And PET
por: Stoykow, Christian, et al.
Publicado: (2016)

Prospects of Targeting the Gastrin Releasing Peptide Receptor and Somatostatin Receptor 2 for Nuclear Imaging and Therapy in Metastatic Breast Cancer
por: Dalm, Simone U., et al.
Publicado: (2017)

Targeting the gastrin-releasing peptide receptor pathway to treat cognitive dysfunctionassociated with Alzheimer’s Disease
por: Roesler, Rafael, et al.
Publicado: (2007)

Photoacoustic signal enhancement in dual-contrast gastrin-releasing peptide receptor-targeted nanobubbles
por: Zhao, Shensheng, et al.
Publicado: (2023)

Gastrin-releasing peptide, substance P and cytokines in rheumatoid arthritis
por: Green, Paul G
Publicado: (2005)

How Gastrin-Releasing Peptide Opens the Spinal Gate for Itch
por: Pagani, Martina, et al.
Publicado: (2019)

A Novel Reagent for Radioiodine Labeling of New Chemical Entities (NCEs) and Biomolecules
por: Kumar, Krishan, et al.
Publicado: (2021)

Overexpression of Gastrin-Releasing Peptide Receptors in Tumor-Associated Blood Vessels of Human Ovarian Neoplasms
por: Fleischmann, Achim, et al.
Publicado: (2007)

Spinal gastrin releasing peptide receptor expressing interneurons are controlled by local phasic and tonic inhibition
por: Freitag, Fabio B., et al.
Publicado: (2019)

Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons
por: Takanami, Keiko, et al.
Publicado: (2021)

Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy
por: Peng, Shuman, et al.
Publicado: (2023)

Facilitation of the inhibitory transmission by gastrin-releasing peptide in the anterior cingulate cortex
por: Cao, XiaoYan, et al.
Publicado: (2010)

Oxygen, Gastrin-Releasing Peptide, and Pediatric Lung Disease: Life in the Balance
por: Sunday, Mary E.
Publicado: (2014)

Inhibition of Gastrin-Releasing Peptide Attenuates Phosphate-Induced Vascular Calcification
por: Park, Hyun-Joo, et al.
Publicado: (2020)

Pro-Gastrin-Releasing Peptide as a Biomarker in Lung Neuroendocrine Neoplasm
por: Rosiek, Violetta, et al.
Publicado: (2023)

Preclinical assessment of IRDye800CW‐labeled gastrin‐releasing peptide receptor‐targeting peptide for near infrared‐II imaging of brain malignancies
por: Zhang, Yuan, et al.
Publicado: (2023)

GRPR-targeted Protein Contrast Agents for Molecular Imaging of Receptor Expression in Cancers by MRI
por: Pu, Fan, et al.
Publicado: (2015)

Positron Emission Tomography (PET) Imaging of Prostate Cancer with a Gastrin Releasing Peptide Receptor Antagonist - from Mice to Men
por: Wieser, Gesche, et al.
Publicado: (2014)

Gastrin releasing peptide receptor targeted nano-graphene oxide for near-infrared fluorescence imaging of oral squamous cell carcinoma
por: Li, Ran, et al.
Publicado: (2020)

Targeting the Gastrin-Releasing Peptide Receptor (GRP-R) in Cancer Therapy: Development of Bombesin-Based Peptide–Drug Conjugates
por: Gomena, Jacopo, et al.
Publicado: (2023)

Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer
por: Abouzayed, Ayman, et al.
Publicado: (2020)

Gastrin-releasing peptide receptors in the central nervous system: role in brain function and as a drug target
por: Roesler, Rafael, et al.
Publicado: (2012)

Involvement of Gastrin-Releasing Peptide Receptor in the Regulation of Adipocyte Differentiation in 3T3-L1 Cells
por: Kim, Mi-Kyoung, et al.
Publicado: (2018)

Sexual Experience Induces the Expression of Gastrin-Releasing Peptide and Oxytocin Receptors in the Spinal Ejaculation Generator in Rats
por: Oti, Takumi, et al.
Publicado: (2021)

Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors
por: Roosenburg, Susan, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_dku3m8a3fdp72nh1m0gdcpbdlu