Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes

Astrocytes play vital roles in neurological disorders. The use of human induced pluripotent stem cell (iPSC)-derived astrocytes provides a chance to explore the contributions of astrocytes in human diseases. Here we review human iPSC-based models for neurological disorders associated with human astr...

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Detalles Bibliográficos
Autores principales: Suga, Mika, Kondo, Takayuki, Inoue, Haruhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720891/
https://www.ncbi.nlm.nih.gov/pubmed/31398826
http://dx.doi.org/10.3390/ijms20163862
Descripción
Sumario:Astrocytes play vital roles in neurological disorders. The use of human induced pluripotent stem cell (iPSC)-derived astrocytes provides a chance to explore the contributions of astrocytes in human diseases. Here we review human iPSC-based models for neurological disorders associated with human astrocytes and discuss the points of each model.

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