Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes

Astrocytes play vital roles in neurological disorders. The use of human induced pluripotent stem cell (iPSC)-derived astrocytes provides a chance to explore the contributions of astrocytes in human diseases. Here we review human iPSC-based models for neurological disorders associated with human astr...

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Detalles Bibliográficos
Autores principales: Suga, Mika, Kondo, Takayuki, Inoue, Haruhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720891/
https://www.ncbi.nlm.nih.gov/pubmed/31398826
http://dx.doi.org/10.3390/ijms20163862
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author Suga, Mika
Kondo, Takayuki
Inoue, Haruhisa
author_facet Suga, Mika
Kondo, Takayuki
Inoue, Haruhisa
author_sort Suga, Mika
collection PubMed
description Astrocytes play vital roles in neurological disorders. The use of human induced pluripotent stem cell (iPSC)-derived astrocytes provides a chance to explore the contributions of astrocytes in human diseases. Here we review human iPSC-based models for neurological disorders associated with human astrocytes and discuss the points of each model.
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spelling pubmed-67208912019-09-10 Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes Suga, Mika Kondo, Takayuki Inoue, Haruhisa Int J Mol Sci Review Astrocytes play vital roles in neurological disorders. The use of human induced pluripotent stem cell (iPSC)-derived astrocytes provides a chance to explore the contributions of astrocytes in human diseases. Here we review human iPSC-based models for neurological disorders associated with human astrocytes and discuss the points of each model. MDPI 2019-08-08 /pmc/articles/PMC6720891/ /pubmed/31398826 http://dx.doi.org/10.3390/ijms20163862 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Suga, Mika
Kondo, Takayuki
Inoue, Haruhisa
Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
title Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
title_full Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
title_fullStr Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
title_full_unstemmed Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
title_short Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
title_sort modeling neurological disorders with human pluripotent stem cell-derived astrocytes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720891/
https://www.ncbi.nlm.nih.gov/pubmed/31398826
http://dx.doi.org/10.3390/ijms20163862
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